Phase 3 Huntington's Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You must be willing and able to sign a consent form before the study begins
- You must be able to walk and move around independently, and be between 21 and 70 years old (inclusive) on the day you sign the consent form
- You must have a confirmed genetic diagnosis of Huntington's disease (HD), with a specific genetic marker (called a CAG repeat) of 40 or above — this must have been confirmed by a genetic test before the screening process
- You must meet all four of the following HD-related assessment scores: a daily living independence score of 90 or above, a functional capacity score of 13, a movement/motor symptom score between 7 and 25, and a combined age-and-genetics score (called CAP100) of 70 or above (confirm with trial site)
Who may not be able to join:
- You have previously had gene therapy, a cell transplant, or any experimental brain surgery to treat HD
- You have signs of active hepatitis B or hepatitis C infection, or you have HIV (confirm with trial site)
- You have a history of certain serious heart rhythm problems or electrical heart abnormalities, or a personal or family history of a specific inherited heart condition called Long QT Syndrome or Torsade de Pointes
- Women who are physically capable of becoming pregnant are not eligible unless they have had a specific surgical procedure (such as removal of both ovaries, a full hysterectomy, or removal of both fallopian tubes) at least six weeks before starting the study treatment, or are using a highly effective form of contraception during the study and for 8 months after stopping treatment (confirm with trial site)
- Women who are currently pregnant or breastfeeding are not eligible
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: 1-888-669-6682
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Change from Baseline in cUHDRS score
Can't join this trial?
Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.