Phase 2 Asthma Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People aged 18 to 75 years, of any gender
• People who have been diagnosed with bronchial asthma according to Chinese clinical guidelines — including those newly diagnosed, or those diagnosed with asthma during childhood or adolescence whose symptoms have become noticeably worse in adulthood
• People whose breathing test results before the trial show lung function within a specific moderate range (FEV1 between 60% and 85% of the expected value for their age and size)
• People whose breathing tests show variable airflow limitation — confirmed by at least one of several possible tests, such as a bronchodilator response test, a bronchial challenge test, or peak flow monitoring over 7 days (confirm with trial site for which test applies)
• People who have voluntarily signed a consent form agreeing to take part

Who may not be able to join:

• People who are unable to correctly use a nebuliser (inhaled mist device), cannot tolerate this type of medication delivery, or do not pass inhaler training
• People who have other lung conditions such as chronic obstructive pulmonary disease, bronchiectasis, pulmonary fibrosis, or tuberculosis — where, in the investigator's judgement, asthma is still the main condition (confirm with trial site)
• People with other significant conditions that affect lung function, such as diseases of the pleura, chest wall, diaphragm, or certain muscle conditions
• People with a history of serious heart conditions — such as heart failure, coronary artery disease, heart attack, irregular heartbeat, or uncontrolled high blood pressure — where the investigator judges this would pose a risk or affect the results
• People with an overactive thyroid (hyperthyroidism) that the investigator considers unsuitable for trial participation
• People with a history of serious blood, liver, psychiatric, kidney, or other diseases that the investigator believes would pose a risk or affect the results
• People who have had a cancer diagnosis in the past five years (exceptions may apply for certain treated cancers — confirm with trial site)
• People who have had, or are expected to have, a solid organ or bone marrow transplant within the coming year
• People with low potassium levels in their blood at the time of screening
• People with Type 1 diabetes, or Type 2 diabetes that is not well controlled (based on a fasting blood sugar test at screening)
• People found to have a fungal infection of the mouth, throat, or food pipe (candidiasis) at or before the start of the trial
• People with abnormal liver or kidney function based on blood tests at screening
• People with certain active or significant hepatitis B or C infections, a positive HIV test, or a history of AIDS
• People with a known allergy to inhaled corticosteroids or to salbutamol (a common reliever medication)
• People who have had a respiratory infection, sinus infection, or middle ear infection within 4 weeks before screening or during the run-in period, where the investigator believes this affected their asthma treatment or condition
• People who had an asthma flare-up requiring steroid tablets or injections within 4 weeks before screening or during the run-in period, or who require ongoing oral steroid treatment for asthma
• People who have taken certain strong medications that affect how the body processes drugs (strong CYP3A4 inhibitors, such as ritonavir or ketoconazole) within 4 weeks before starting the trial, or who would need to take these during the trial
• People who stopped smoking less than 1 year before screening, or who have a smoking history of more than 10 pack-years — this includes cigarettes, cigars, pipe tobacco, and e-cigarettes
• People with a history of drug, substance, or alcohol misuse within the 2 years before screening (alcohol misuse is defined as more than 2 standard units per day on average)
• Women who are pregnant, breastfeeding, or planning to become pregnant during the trial
• People who have taken part in another clinical trial within 1 month before screening
• Anyone else the investigator considers unsuitable for any other reason

Important: Always verify eligibility with the trial site directly before applying.