Phase 1 Asthma Trial, Recruiting NCT07330778 Sponsor: Celldex Therapeutics Condition: Asthma
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Phase 1 Asthma Trial, Recruiting

NCT07330778
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are 18 years of age or older (any gender)
  • You have been diagnosed with mild to moderate asthma for at least 12 months
  • Your lung function (measured by a breathing test) is at or above 70% of the expected normal level before using an inhaler
  • Your airways show a meaningful improvement of at least 12% and 200mL in breathing capacity after using an inhaler
  • If you are able to have children (male or female), you must agree to use contraception during the study and for 150 days after treatment ends
  • You are willing and able to follow all study rules and attend all required visits

Who may not be able to join:

  • You are currently pregnant or breastfeeding
  • You have a lung or breathing condition other than asthma
  • You have a condition (other than asthma) that causes high levels of a certain type of white blood cell called eosinophils in your body (confirm with trial site)
  • You have been hospitalised or needed steroid tablets/pills for your asthma in the past 6 months
  • You have ever needed a breathing machine (ventilator) to help you breathe due to asthma
  • You currently have nasal polyps (small growths inside the nose)
  • Your asthma is currently severe or poorly controlled
  • You have smoked or vaped in the past 12 months
  • You have tuberculosis, hepatitis B, hepatitis C, or HIV
  • You have received certain immune-modifying treatments (biologics) in the past 3 months (confirm with trial site)
  • You have previously received specific treatments called TSLP or KIT inhibitors, such as tezepelumab or briquilimab (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: 844-723-9363

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Sponsor
Celldex Therapeutics
Registry
ClinicalTrials.gov
Start date
1 June 2026
Est. completion
1 March 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

To evaluate the safety and tolerability profile of CDX-622 in adults with mild to moderate asthma.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov