Phase 2 Lymphoma Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are an adult diagnosed with a type of T-cell lymphoma (including PTCL, T-PLL, ATLL, or CTCL of any subtype) and your cancer is in partial or complete remission between 35 and 120 days after a stem cell transplant (either from your own cells or a donor's cells)
• You are generally well enough to carry out light activity and care for yourself (a doctor will assess this using a standard scale)
• Your blood counts are at an acceptable level — including white blood cells, platelets, and red blood cells — without needing supportive injections or transfusions for at least 3 days
• Your liver, kidneys, and lungs are functioning well enough based on blood and oxygen tests
• You are able to swallow and digest medication taken by mouth or through a feeding tube
• You agree to use an effective form of birth control throughout the study (if you are a woman who could become pregnant or a man who could father a child)
• You are able to read and sign a consent form agreeing to take part in the study

Who may not be able to join:

• You have a specific subtype of lymphoma called ALK-positive or DUSP22-positive ALCL with a low risk score and are in your first complete remission
• Your cancer has gotten worse after the transplant, or you have received any other cancer treatment after the transplant (radiation therapy is allowed)
• Your cancer previously got worse while you were being treated with a drug called Ruxolitinib
• You have a transplant-related immune complication called graft-versus-host disease (GvHD) that requires treatment with systemic medications
• You have an active infection that is not under control
• You have an active blood vessel clotting condition that requires treatment (confirm with trial site)
• You have had a liver complication called veno-occlusive disorder after your transplant
• You are taking blood thinners or anti-clotting medications that cannot safely be stopped if your platelet levels drop
• You have a history of a life-threatening bleed, meaning one that required surgery or affected your brain or spinal cord
• You are pregnant or currently breastfeeding (pregnancy testing may be required if applicable)
• You have an uncontrolled infection with Hepatitis B, Hepatitis C, HIV, tuberculosis, or certain fungal infections
• You have taken part in another clinical trial or received an experimental drug within the past 4 weeks
• You have had a serious side effect from your stem cell transplant (rated severe or worse) that has not improved sufficiently
• You have had a heart attack or stroke within the past year
• You have any other uncontrolled health condition that the trial doctor feels would put you at risk

Important: Always verify eligibility with the trial site directly before applying.