Phase 3 Narcolepsy Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• Your body weight is in a healthy range for your height, with a BMI (body mass index) between 18 and 40.
• You have been officially diagnosed with Narcolepsy Type 1 (a sleep disorder that causes extreme daytime sleepiness and sudden muscle weakness) using recognised medical guidelines.
• You either carry a specific gene variant linked to narcolepsy (HLA-DQB1*06:02), or a special test of your spinal fluid has shown very low levels of a brain chemical called hypocretin-1 (confirm with trial site).

Who may not be able to join:

• You have a medical condition other than narcolepsy with cataplexy that also causes excessive daytime sleepiness.
• You have a history of heart attack, significant liver disease, thyroid disease, coronary artery disease, irregular heart rhythm, heart failure, or serious ongoing problems with your heart, lungs, kidneys, or digestive system.
• You have had a stomach or digestive condition in the last 6 months that could affect how your body absorbs medication.
• You have been diagnosed with cancer at any point in the last 5 years.
• You have a significant history of head injury or head trauma.
• You have a history of epilepsy, seizures, or convulsions (except for a single fever-related seizure during childhood).
• You have a history of stroke, a mini-stroke within the last 5 years, a brain aneurysm, or an abnormal tangle of blood vessels in the brain.

Important: Always verify eligibility with the trial site directly before applying.