Glaucoma Trial, Recruiting NCT07364929 Sponsor: National University of Singapore Condition: Glaucoma
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Glaucoma Trial, Recruiting

NCT07364929
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

For people with glaucoma:

  • People who have been diagnosed with a specific type of glaucoma called primary open-angle glaucoma, where a recent vision field test showed results better than -12 dB in at least one eye
  • People whose central (straight-ahead) vision is still intact
  • People between 45 and 75 years old
  • People whose best-corrected vision (with glasses or contact lenses) is better than 6/12
  • People who speak English

For healthy participants (no glaucoma):

  • People between 50 and 70 years old
  • People whose best-corrected vision (with glasses or contact lenses) is better than 6/12
  • People with a normal eye examination
  • People who speak English

Who may not be able to join:

  • People with short-sightedness (myopia) stronger than -8.00 diopters
  • People who have had complicated eye surgery in the past
  • People taking a type of eye drop called alpha-adrenergic agonists, or any other medications that may affect how the pupil responds to light
  • People who have or have had certain eye conditions, such as age-related macular degeneration, diabetic eye disease, significant eye injury, or conditions that affect eye movement (confirm with trial site)
  • People with cataracts graded at a moderate-to-advanced level (NS3 or above), or a specific type of cataract at the back of the lens (posterior subcapsular cataract)
  • People with a clinically diagnosed psychiatric or neurological condition, including memory problems or dementia
  • People with a diagnosed mood disorder
  • People who have worked night shifts in the past three months, are currently using sleeping pills, or have travelled across time zones within the past month
  • People diagnosed with obstructive sleep apnea
  • People with abnormal hearing function
  • People with impaired colour vision
  • Women who have not yet reached menopause (last menstrual period less than one year ago), where applicable
  • People with glaucoma in only one eye, glaucoma present from birth, optic nerve damage not caused by glaucoma, or abnormal central vision
  • People with diabetes who are currently on treatment for it

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 14 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Raymond P. Najjar, PhD, National University of Singapore

Phone: +65 65165474

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
National University of Singapore
Registry
ClinicalTrials.gov
Start date
5 September 2025
Est. completion
1 October 2026

Where this trial is recruiting

🇸🇬 Singapore

Primary endpoints

Subjective Sleep Quality; Subjective Daytime Sleepiness; Depressive Symptoms; Global Cognitive Function; Global Cognitive Function during light exposure; Median Reaction Time; Vigilance Lapses; Long Reation Time Lapses; Anticipatory Responses; Sustained Attention Variability; Associative Learning; Processing Speed; Visual Attention Allocation; Eye-Movement Behavior; Selective Attention; Auditory Discrimination Performance; Task-Evoked Pupillary Responses; Pupillary Responses to Shapes; Objective sleepiness; Risk Taking Behavior; Subjective Sleepiness, Mood, and Wellbeing; Sleep Quantity; Sleep...

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 14 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov