Phase 2 Prostate Cancer Trial, Recruiting NCT07365423 Sponsor: Swiss Cancer Institute Condition: Prostate Cancer
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Phase 2 Prostate Cancer Trial, Recruiting

NCT07365423
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have already completed a full course of treatment for localised prostate cancer (such as surgery to remove the prostate, radiation therapy, or brachytherapy), and where standard curative treatment options have been exhausted
  • People who have previously had targeted radiation treatment (called SBRT) for a small number of visible cancer spread sites, as long as the prostate-specific antigen (PSA) blood marker has continued to rise after that treatment
  • People whose testosterone levels are at or above normal non-castrate levels (at least 5 nmol/l); previous hormone-lowering treatment is allowed as long as testosterone levels have returned to normal before joining the trial
  • People who show no signs of cancer that has spread to distant parts of the body, based on standard scans (CT scan and bone scan) or a specialised scan called a PSMA PET CT
  • People who have enlarged lymph nodes detected on a PSMA PET CT scan, provided those lymph nodes are below a certain size threshold depending on their location in the body (confirm with trial site for exact size limits)
  • People whose PSA blood level is 1 ng/ml or higher after prostate removal surgery, or 2 ng/ml or more above their lowest recorded PSA level after radiation therapy, with testosterone at normal levels; a rising PSA must be confirmed by at least two measurements taken at least two weeks apart
  • People who have declined starting hormone therapy and/or a type of medication called an androgen receptor pathway inhibitor (ARPI), or whose treating doctor has assessed that starting these treatments is not immediately necessary

Who may not be able to join:

  • People who have a pre-existing known liver disease, whether long-term (chronic) or short-term (acute)
  • People who have a known history of systemic lupus erythematosus or any form of lupus, including lupus affecting the skin, lupus caused by medication, or lupus affecting the kidneys
  • People whose prostate cancer is of a rare type known as pure neuroendocrine or small-cell variant (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 12 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Stefanie Fischer, PD MD, HOCH Health Ostschweiz

Phone: +41 31 389 91 91

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Swiss Cancer Institute
Registry
ClinicalTrials.gov
Start date
1 May 2026
Est. completion
1 February 2028

Where this trial is recruiting

🇨🇭 Switzerland

Primary endpoints

Prostate specific antigen Progression-free rate (PSA-PFR)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 12 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov