Osteoarthritis Trial, Recruiting NCT07370480 Sponsor: CEN Biotech Condition: Osteoarthritis
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Osteoarthritis Trial, Recruiting

NCT07370480
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with knee osteoarthritis at a moderate to severe level (stages 2 to 4), confirmed by a knee X-ray taken within the past 3 years.
  • People whose knee osteoarthritis causes significant difficulty with physical activities, based on a standard questionnaire score (WOMAC physical function score of 30 or above out of 100).
  • People who have signed a consent form agreeing to take part in the trial.
  • People who have health insurance coverage.

Who may not be able to join:

  • People who have medical conditions that make spa-based water treatments (such as baths, water jets, or massage) unsafe for them — including active cancer, serious heart, liver or kidney problems, open leg ulcers, immune system conditions, certain vein or skin infections, active blood clots, or significant behavioural disorders, among others (confirm with trial site).
  • People who have long-term pain caused by conditions other than osteoarthritis, such as rheumatoid arthritis, lupus, psoriatic arthritis, ankylosing spondylitis, or fibromyalgia.
  • People who are already scheduled to have knee surgery within the next 7 months.
  • People who have had spa therapy in the past 6 months, or who have received a corticosteroid injection into the knee joint in the past 90 days, or who have had hyaluronic acid, other joint lubricant treatments, or platelet-rich plasma (PRP) injections in the past 6 months.
  • People who have plans to attend a spa treatment for any other reason between joining the trial and the final visit.
  • People who live more than 30 kilometres from Enghien-les-Bains at the time the spa treatment takes place.
  • Women who are able to become pregnant and are not using an approved form of hormonal contraception, or who plan to stop using contraception within the next 7 months.
  • People who are unlikely to be able to follow the trial's requirements or attend all required visits, or who are unable to read or understand French.
  • People who are under legal guardianship or who are already taking part in another clinical trial, or who are within a restricted period following a previous clinical trial.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 12 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Magali Ballard, MD

Phone: +33380680511

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
CEN Biotech
Registry
ClinicalTrials.gov
Start date
27 January 2026
Est. completion
10 February 2027

Where this trial is recruiting

🇫🇷 France

Primary endpoints

Minimal Clinically Important Improvement (MCII) at 6 months; Minimal Clinically Important Improvement (MCII) at 6 months

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 12 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov