Phase 3 Stroke Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People aged 18 years or older.
• People who have had an acute ischemic stroke (a stroke caused by a blocked blood vessel) in a specific part of the brain's blood supply, confirmed by symptoms and medical imaging.
• People whose stroke symptoms started, or who were last known to be well, more than 24 hours but no more than 7 days before joining the trial.
• People whose stroke has been confirmed through specialised brain vessel imaging to be caused by a narrowing or hardening of arteries inside the skull, with other causes such as heart-related clots ruled out.
• People whose stroke severity falls within a specific moderate range on a standard medical scoring scale at the time of joining (confirm with trial site).
• People, or their legal representative, who have signed a consent form agreeing to take part.

Who may not be able to join:

• People who are planned to receive clot-dissolving treatment (either through a vein or a procedure inside a blood vessel).
• People with bleeding inside the brain confirmed by a CT scan.
• People whose stroke is confirmed or suspected to have been caused by a clot travelling from the heart.
• People with a history of atrial fibrillation (an irregular heart rhythm), or whose current heart tracing shows atrial fibrillation.
• People whose stroke was caused by other specific conditions such as Moyamoya disease, a torn artery wall, or inflamed arteries.
• People whose brain imaging shows the area of stroke damage covers more than half of a single brain lobe.
• People who have a known reason why antiplatelet medicines (blood-thinning tablets such as aspirin) cannot be used, including bowel bleeding, stomach or gut bleeding, or other bleeding conditions.
• People with a known allergy or sensitivity to aspirin.
• People who are expected to need blood-thinning (anticoagulant) medication during the trial for conditions such as atrial fibrillation, a mechanical heart valve, blood clots in the legs or lungs, or related conditions.
• People with certain serious health conditions including cancer, regular kidney dialysis, severely reduced kidney function, or severely reduced liver function (confirm with trial site for specific test values).
• People with severe heart failure classified as Class III or IV on a standard medical scale.
• People with a serious non-heart-related illness where survival is estimated at less than 6 months.
• People who have had a new stroke affecting both the front and back areas of the brain's blood supply at the same time.
• People who are not able to complete the required follow-up appointments and assessments.
• People with other known neurological (brain or nerve) conditions that may affect follow-up results.
• People who are currently taking part in another treatment-based clinical trial that has not yet been completed.
• People whom the trial doctors consider unsuitable for other reasons.

Important: Always verify eligibility with the trial site directly before applying.