Schizophrenia Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You (or your caregiver or legal guardian) must be willing and able to sign a consent form agreeing to take part in the study.
- You must be 18 years old or older and able to take part in regular medical care and follow-up visits, in your doctor's opinion.
- You must have schizophrenia, and your doctor must have already decided — separately from this study — to treat you with the medication xanomeline and trospium chloride (also called KarXT).
- You must either have started taking KarXT within the last 16 weeks and plan to stop your previous antipsychotic medication, OR currently be on a stable dose of one or more antipsychotic medications and have a plan to switch to KarXT (you can be enrolled even while in the process of tapering off your previous medication).
- Other psychiatric medications (such as antidepressants or mood stabilizers) are allowed, and it is recommended that these stay at the same dose throughout the study.
Who may not be able to join:
- You have previously tried KarXT and stopped taking it for any reason before the study begins.
- You have taken part in another clinical trial within the last 30 days, or plan to join another interventional trial during this study.
- You have a known allergy to xanomeline or trospium chloride, a history of or high risk of difficulty urinating, stomach emptying problems, certain liver problems, or a specific type of eye condition called narrow-angle glaucoma.
- In your doctor's opinion, your psychiatric or physical health condition is not stable enough to safely switch to KarXT.
- You are currently pregnant, planning to become pregnant, or breastfeeding.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Bristol Myers Squibb, Bristol-Myers Squibb
Phone: 855-907-3286
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Treatment titration and switch regimens as described by the prescribing clinician
Can't join this trial?
Data last synced from ClinicalTrials.gov: 8 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.