Osteoarthritis Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who are 65 years of age or older
- People who are scheduled to have a single knee replacement surgery (on one knee only) for the first time, under a standard anaesthetic plan
- People whose overall health has been assessed by a doctor as falling within a moderate range of physical fitness (confirm with trial site for exact classification)
- People who are able to understand what the study involves and are willing to sign a written consent form
Who may not be able to join:
- People for whom nerve-blocking injections near the surgical site are not medically appropriate — for example, due to a skin infection at the injection site, a blood clotting problem, or personal unwillingness to have the procedure
- People with a known allergy or sensitivity to a group of local anaesthetic medicines called amide anaesthetics, or to the medications dexamethasone or dexmedetomidine
- People who have been taking opioid-based pain medicines regularly, or at higher doses (more than 30 mg of oral morphine or equivalent per day), within the past three months
- People with seriously reduced liver or kidney function
- People with significant memory or thinking difficulties that would make it hard to reliably report pain levels during the study
- People who are already taking part in another clinical trial that involves pain management or pain medicines
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Malgorzata Reysner, MD PhD, Poznan University of Medical Sciences
Phone: +48 61 873 83 03
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Cumulative opioid consumption in the first 24 hours after surgery
Can't join this trial?
Data last synced from ClinicalTrials.gov: 15 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.