Phase 2 Lymphoma Trial, Recruiting NCT07387471 Sponsor: AbbVie Condition: Lymphoma
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Phase 2 Lymphoma Trial, Recruiting

NCT07387471
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have a confirmed diagnosis of Waldenström macroglobulinemia (WM) or lymphoplasmacytic lymphoma (LPL), based on recognised international medical classification systems.
  • People who have already received at least one standard treatment for WM or LPL.
  • People whose disease is measurable, meaning either a specific protein called IgM is detected at a high enough level in the blood, or tumour spots of a certain size are visible on a scan (confirm with trial site for exact measurements that apply to each situation).
  • People whose doctor has determined that whole-body cancer treatment is needed for their WM or LPL.
  • People who are reasonably active and able to carry out daily activities, as assessed using a standard medical scale (confirm with trial site).
  • People whose liver, kidneys, and bone marrow are functioning well enough to meet the trial's requirements (confirm with trial site for specific thresholds).

Who may not be able to join:

  • People who have previously been treated with a drug called venetoclax or any other therapy that targets the same protein (BCL-2).
  • People who have an active infection that is not under control.
  • People who have a known bleeding disorder, such as von Willebrand's disease or haemophilia.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: ABBVIE INC., AbbVie

Phone: 844-663-3742

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Registry
ClinicalTrials.gov
Start date
17 March 2026
Est. completion
1 July 2028

Where this trial is recruiting

🇯🇵 Japan

Primary endpoints

Number of Participants with Major Response; Number of Participants with Major Response in participants with IgM >= 500 mg/dL

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov