Phase 2 Macular Degeneration Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who meet the trial's required age range (confirm with trial site for specific age details)
• People who have geographic atrophy in both eyes caused by age-related macular degeneration (AMD), confirmed by a specialist reading centre
• People whose affected area in the eye meets a specific size range, measured using a special retinal imaging technique called fundus autofluorescence
• People whose vision — including vision in low-light conditions — falls within the required range, tested using standardised eye charts
• People whose retinal sensitivity (how well the retina responds to light) meets the required level, measured by a specialised test called microperimetry
• People who have enough useful vision in their other eye to allow safe navigation
• People who have historical retinal scan records available that can be used to track changes over time
• People who meet the study's requirements around reproductive status and use of contraception, where this applies
• People who are able and willing to give informed consent and follow all study procedures

Who may not be able to join:

• People whose macular or retinal damage is caused by something other than AMD
• People who have, or have previously had, the "wet" form of AMD (also called choroidal neovascularisation)
• People who have had surgery, laser treatment, or other procedures on the eye being studied that could affect the results
• People who have previously received treatments directed at AMD or injections into the study eye, except for certain approved nutritional supplements
• People who have previously been treated with a type of medication called a complement inhibitor
• People who have eye infections, inflammation, other eye conditions, or clouding in the eye that would affect safety or interfere with retinal imaging
• People with uncontrolled glaucoma, diabetic eye disease, or a significant uncorrected refractive error (such as very high short- or long-sightedness)
• People who are missing the eye's natural lens (aphakia) or have a compromised lens capsule, unless the protocol specifically allows for this
• People with certain serious physical health or mental health conditions that could increase risk or make it difficult to follow the study requirements
• People who have recently taken part in another clinical trial or have been exposed to an experimental treatment
• People who, in the treating doctor's judgement, have any condition that would make participation unsafe

Important: Always verify eligibility with the trial site directly before applying.