Osteoarthritis Trial, Recruiting NCT07397806 Sponsor: Steadman Philippon Research Institute Condition: Osteoarthritis
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Osteoarthritis Trial, Recruiting

NCT07397806
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People between the ages of 40 and 85 years old
  • People who are able to walk around both at home and in the community
  • People who have been diagnosed with knee osteoarthritis in one or both knees, confirmed by imaging at a moderate to severe level (Kellgren-Lawrence grade II–IV) (confirm with trial site)
  • People whose more-affected knee has a pain level of 3 to 10 out of 10, and whose other knee has a pain score at least 2 points lower, based on the worst pain felt in the past week
  • People who are able to give their own consent to participate and are willing to follow all study procedures and attend all assessments

Who may not be able to join:

  • People who have planned surgery on either knee at any point during the study period, including before and after training assessments
  • People who have had a surgical procedure (such as arthroscopy, microfracture, or removal of knee cartilage) on the more-affected knee within the past 6 months
  • People who have received steroid or hyaluronic acid injections into the more-affected knee within the past 12 weeks
  • People who have planned steroid or hyaluronic acid injections into either knee at any point during the study period
  • People who have previously had a full or partial knee replacement in the more-affected knee
  • People who have had a blood disorder (such as blood clots, hemophilia, leukemia, or myeloma) within the past 2 years, or who have or have had cancer within the past 2 years (excluding treated basal or squamous cell skin cancer)
  • People with a current diagnosis of fibromyalgia
  • People with an active autoimmune disease or a history of inflammatory joint conditions such as rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, or reactive arthritis (some mild or well-controlled conditions may be considered — confirm with trial site)
  • People with other joint conditions such as gout, osteonecrosis, joint infection, Paget's disease, Ehlers-Danlos Syndrome, or other listed joint diseases
  • People whose overall health, medical history, or test results are considered by the lead researcher to make participation risky or unsuitable
  • People who have used opioid pain medications within the past 8 weeks and are not willing to stop taking them for the full duration of the study

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 19 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Scott Tashman, PhD, Steadman Philippon Research Institute

Phone: 970-401-8717

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Steadman Philippon Research Institute
Registry
ClinicalTrials.gov
Start date
11 September 2025
Est. completion
31 May 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Pain: Numerical Rating Scale; Pain and Function: WOMAC

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 19 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov