Motor Neurone Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People aged between 21 and 75 years old.
- People (in the "control" group) who are scheduled for planned neck spine surgery that includes a specific procedure to relieve pressure on the spinal cord (called a decompressive laminectomy), where nerve monitoring is already being done as a routine part of their surgery.
- People (in the "stroke" group) who have had a single stroke — either a blockage-type or bleeding-type — more than 6 months before joining the trial, and who have weakness on one side of the body as a result, and who are either having a spinal stimulator lead placed in the neck area or are scheduled for the same type of planned neck spine surgery described above, with routine nerve monitoring included.
Who may not be able to join:
- People who have a known nervous system condition other than stroke — such as ALS (Lou Gehrig's disease), spinal muscular atrophy, spinal cord injury, autoimmune nerve disease, or sensory nerve disorders — that could affect the nerves being studied in the neck area.
- People who are not medically cleared for surgery for any reason, including pregnancy or other health conditions that make surgery unsuitable.
- People who are currently taking medications to reduce muscle stiffness (anti-spasticity medications) or to prevent seizures (anti-epileptic medications).
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Peter C Gerszten, MD, University of Pittsburgh, Neurological Surgery
Phone: 412-647-0958
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Spinal Circuit Excitability
Can't join this trial?
Data last synced from ClinicalTrials.gov: 16 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.