Phase 1 Crohn's Disease and Colitis Trial, Recruiting NCT07401680 Sponsor: University of Alberta Condition: Crohn's Disease and Colitis
Back to Crohns Disease And Colitis

Phase 1 Crohn's Disease and Colitis Trial, Recruiting

NCT07401680
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are 18 years of age or older
  • You are able to give your own consent to participate in the study
  • You have been diagnosed with ulcerative colitis (UC) confirmed through a camera examination of your bowel and tissue samples
  • Your ulcerative colitis is currently active (meaning you are experiencing symptoms)
  • If you are a woman who could become pregnant, you are willing to use an effective form of birth control for at least 4 weeks before starting the study and throughout the entire trial
  • You are willing and able to follow all of the study's required steps and procedures

Who may not be able to join:

  • Your ulcerative colitis is severe enough that you need to be treated in a hospital
  • You have been diagnosed with Crohn's disease or a bowel condition that doctors have not been able to clearly classify
  • You have irritable bowel syndrome (IBS)
  • You had a bowel infection in the 4 weeks before joining the study
  • Scans have shown signs of serious bowel complications, such as a dangerously swollen colon or a hole in the bowel
  • You are already scheduled to have surgery to remove your colon
  • You had abdominal (stomach) surgery in the 60 days before joining the study
  • Your blood tests show a very low level of a type of infection-fighting white blood cell (confirm with trial site)
  • Your blood tests show a very high white blood cell count combined with a fever above 38°C (confirm with trial site)
  • You are currently taking or planning to take another experimental medication or treatment
  • You have a medical condition that is not well controlled, such as a mental health disorder or substance misuse problem
  • You have a serious illness that means you are not expected to live for at least 30 more days
  • You are currently pregnant or breastfeeding
  • You are unwilling to stop taking probiotic supplements (not including food sources like yoghurt)
  • You have taken antibiotics in the 30 days before joining the study, or you are likely to need antibiotic treatment during the trial
  • You have had a faecal microbiota transplant (a procedure involving donor stool) within the 6 months before joining the study
  • The doctor running the trial believes that joining the study would not be in your best interest

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 21 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: 780-492-5257

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Registry
ClinicalTrials.gov
Start date
1 March 2026
Est. completion
1 March 2028

Where this trial is recruiting

🇨🇦 Canada

Primary endpoints

Steroid-free endoscopic remission

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov