Phase 3 Lymphoma Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People aged 21 years or older, of any gender
- People who have been diagnosed with primary vitreoretinal lymphoma (a type of eye cancer) confirmed through a biopsy
- People who have lymphoma cells present in the gel-like fluid inside the eye at the time of screening, or who have had eye surgery to remove that fluid as part of confirming their diagnosis
- People who are willing to take part in the trial and have signed a consent form agreeing to participate
Who may not be able to join:
- People with a known allergy or sensitivity to a medication called methotrexate
- People who have eye surgery planned during the period of the trial
- Women who are pregnant or breastfeeding, or who could become pregnant
- People with existing eye or other health conditions that, in the trial doctor's opinion, could affect how the trial is run or how the results are interpreted (confirm with trial site)
- People who have taken methotrexate as a whole-body (systemic) treatment within one week before starting the trial treatment
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: 781-257-3063
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Proportion of clearance of lymphomatous vitreous cells compared across ICM and monthly ADX-2191 treatment groups after eight weeks of treatment
Can't join this trial?
Data last synced from ClinicalTrials.gov: 9 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.