Phase 3 Alzheimer's Disease Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are able to understand and agree to participate by signing a consent form
• You are 50 years of age or older (any gender)
• You have been diagnosed with healthy aging (no memory problems), mild cognitive impairment (MCI), or Alzheimer's disease (AD), based on recognised medical diagnostic standards
• You are able to undergo brain MRI and PET scans
• If you are a woman who could still become pregnant, you agree to use an effective form of contraception during the study and for 3 months afterwards; male participants also agree to use contraception during the study and for 3 months afterwards

Who may not be able to join:

• You have been diagnosed with an uncommon or atypical form of Alzheimer's disease as defined by specific 2014 medical guidelines (confirm with trial site)
• You have signs of a condition called frontotemporal degeneration, which mainly affects behaviour, decision-making, or language
• You have core symptoms of Lewy body dementia, such as fluctuating attention, repeated vivid visual hallucinations, or Parkinson's-like movement symptoms
• You are currently experiencing significant mental health or psychiatric illness that may prevent you from completing the scans
• Your MRI shows major brain abnormalities, such as a large stroke or a growth inside the skull
• You have claustrophobia or cannot tolerate scanning procedures for any reason
• You have a history of alcohol or drug misuse or dependency
• You have had an allergic reaction to the study drug or any of its ingredients
• You are currently pregnant or breastfeeding
• You have taken part in a non-vaccine Alzheimer's or dementia clinical trial in the past 3 months, received antibody (passive immunotherapy) treatment for Alzheimer's or dementia in the past 6 months, previously received an Alzheimer's or dementia vaccine at any time, or joined any new drug clinical trial in the past 30 days
• You currently have a serious illness — such as an infection, hormonal or metabolic condition, or significant problems with your heart, liver, lungs, or kidneys — that the research team believes could be harmful to you or affect the study results
• You currently have a condition or are taking a medication known to affect the heart's electrical activity in a specific way (called QT interval prolongation), such as certain heart rhythm medications (confirm with trial site)
• There are any other reasons the research team considers make participation unsuitable for you

Important: Always verify eligibility with the trial site directly before applying.