Macular Degeneration Trial, Recruiting NCT07423429 Sponsor: Nantes University Hospital Condition: Macular Degeneration
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Macular Degeneration Trial, Recruiting

NCT07423429
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults aged 18 or older who have the "wet" (neovascular) form of age-related macular degeneration (a condition where abnormal blood vessels grow under the retina)
  • People who have been receiving injections into the eye (called anti-VEGF therapy) to treat this condition for more than one year
  • People whose treating doctor switched their treatment to a specific medication called aflibercept 8 mg before July 31, 2025
  • People who were receiving those eye injections at intervals of less than 12 weeks before the switch to aflibercept 8 mg

Who may not be able to join:

  • People with severe short-sightedness, defined by specific eye measurements (confirm with trial site)
  • People with a condition called angioid streaks, which involves crack-like lines in a layer at the back of the eye
  • People with moderate or severe damage to the blood vessels in the eye caused by diabetes (diabetic retinopathy)
  • People with a history of fluid build-up in the central part of the retina related to diabetes (diabetic macular edema)
  • People with a history of uveitis, which is inflammation inside the eye
  • People with a history of a blocked vein in the retina (retinal vein occlusion)
  • People with a history of a specific inherited eye condition affecting the central retina called pseudovitelliform macular dystrophy
  • People who are under a formal legal guardianship or curatorship arrangement
  • Women who are pregnant or currently breastfeeding

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: 02 40 08 34 01

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
20 February 2026
Est. completion
20 October 2026

Where this trial is recruiting

🇫🇷 France

Primary endpoints

Change in intravitreal injection interval

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov