Phase 3 Stroke Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who have atrial fibrillation (an irregular heartbeat) or atrial flutter that is not caused by a temporary or treatable condition
- People who are at moderate to high risk of having a stroke, based on a medical scoring system that considers factors such as heart failure, high blood pressure, age, diabetes, previous stroke or blood clots, and blood vessel disease
- People whose doctor and care team have jointly decided that the risks of taking blood-thinning medication are greater than the benefits, making that type of medication unsuitable for them
Who may not be able to join:
- People who have an artificial mechanical heart valve (note: a certain type of heart valve procedure called transcatheter aortic valve replacement does not appear to count as an exclusion)
- People who have had a stroke caused by a blocked blood vessel within 2 days before entering the trial
- People who have high blood pressure that is ongoing and not under control, as determined by the treating doctor
- People who have had bleeding in or around the brain within 30 days before entering the trial
- People whose life expectancy is estimated to be less than 12 months
- People who have previously taken part in a clinical study involving a type of medication called a Factor XI inhibitor
- Additional criteria set out in the trial protocol may also apply (confirm with trial site)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Clinical Trial Management, Regeneron Pharmaceuticals
Phone: 844-734-6643
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Time to first occurrence of ischemic stroke or systemic embolism; Time to first occurrence of International Society on Thrombosis and Haemostasis (ISTH) major bleeding
Can't join this trial?
Data last synced from ClinicalTrials.gov: 8 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.