Phase 2 Ovarian Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who are willing to sign a consent form and are able to follow the study schedule and procedures
• Women between 18 and 75 years of age
• People with a physical functioning level rated as 0, 1, or 2 on a standard medical scale called the ECOG scale, meaning they are able to carry out at least some daily activities (confirm with trial site)
• People whose advanced ovarian cancer has been confirmed through tissue or cell testing
• People whose cancer has either not responded to at least two previous standard treatments, who cannot tolerate standard treatments, or for whom no standard treatment is available
• People whose cancer is complicated by a large build-up of fluid in the abdomen (called malignant ascites), with a volume of at least 2,000 mL as shown on ultrasound or CT scan
• People with an expected survival of at least 3 months
• People whose blood counts and organ function (liver, kidneys, and blood clotting) meet specific minimum levels based on recent blood tests, without needing a blood transfusion or certain growth factor medications in the 14 days before enrolling
• People whose side effects from previous treatments have mostly resolved to a mild level before joining (with some exceptions for hair loss and mild nerve-related side effects)

Who may not be able to join:

• People who have previously received any type of cell therapy treatment
• People whose abdominal fluid build-up appears to be divided into separate pockets or compartments, as seen on CT or ultrasound
• People who have received any systemic anti-cancer treatment (such as chemotherapy or targeted therapy) within 3 weeks before the trial procedure
• People who have taken Traditional Chinese herbal medicine with anti-cancer indications within 3 weeks before the trial procedure
• People who have taken oral or injected corticosteroids at a dose of 10 mg per day of prednisone or equivalent, or other immune-suppressing medicines, within 2 weeks before the trial procedure (low-dose inhaled or topical forms may be allowed)
• People who have had major surgery within 4 weeks before screening, or who have major surgery planned during the study
• People who have had another type of cancer within the past 5 years (with some exceptions for certain low-risk skin cancers that have been fully treated)
• People with a history of active or suspected autoimmune or inflammatory disease
• People who have had an organ transplant or a bone marrow/stem cell transplant
• People with certain active infections, including active Hepatitis B, active Hepatitis C, a current infection requiring antibiotic treatment, or HIV
• People who have received a live or weakened live vaccine within 4 weeks before the trial procedure
• People with serious heart or blood vessel conditions, including uncontrolled high blood pressure, recent heart attack or stroke, significant heart failure, or serious abnormal heart rhythms
• People with severe lung disease or significantly reduced lung function based on breathing tests
• People with a known significant neurological or psychiatric condition, such as epilepsy or dementia
• People whom the trial doctors consider unsuitable for other medical reasons, including those who had severe reactions to immunotherapy in the past

Important: Always verify eligibility with the trial site directly before applying.