Phase 2 Lymphoma Trial, Recruiting NCT07439653 Sponsor: TORL Biotherapeutics, LLC Condition: Lymphoma
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Phase 2 Lymphoma Trial, Recruiting

NCT07439653
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with a confirmed type of B-cell non-Hodgkin lymphoma, including (but not limited to) certain specific subtypes such as large B-cell lymphoma (DLBCL), follicular lymphoma (grades 1 to 3A or 3B), mantle cell lymphoma, transformed lymphoma, marginal zone lymphoma, or MALT lymphoma
  • People whose general health and ability to carry out daily activities falls within an acceptable range, as measured by a standard medical scoring system called the ECOG scale (score of 2 or lower)
  • People who have at least one area of lymphoma that is large enough to be measured on a scan, according to standard measurement guidelines called the Lugano criteria
  • People for whom a sample of tumour tissue is available for testing
  • People whose major organs (such as the liver, kidneys, and heart) are functioning at an adequate level

Who may not be able to join:

  • People who have T-cell lymphoma (a different type of lymphoma affecting T-cells rather than B-cells)
  • People who have chronic lymphocytic leukaemia (CLL) or small lymphocytic lymphoma (SLL)
  • People who have Burkitt lymphoma or high-grade B-cell lymphoma
  • People whose lymphoma has spread to the central nervous system (the brain or spinal cord)
  • People who have significant nerve damage or nerve-related symptoms rated above a moderate level (greater than Grade 2 peripheral neuropathy)
  • People with serious medical conditions that are not currently under control
  • People with certain active viral infections (confirm with trial site for specific details)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 19 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: (310) 598-5969

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
TORL Biotherapeutics, LLC
Registry
ClinicalTrials.gov
Start date
31 March 2026
Est. completion
31 March 2029

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Evaluate the safety of TORL-5-700 as a monotherapy; Assess the antitumor activity of TORL-5-700 as monotherapy; Evaluate the safety of TORL-5-700 in combination with other agents; Determine the Maximum Tolerated Dose (MTD); Determine the Recommended Phase 2 Dose (RP2D)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 19 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov