Phase 3 Macular Degeneration Trial, Recruiting NCT07440225 Sponsor: EyeBiotech Ltd. Condition: Macular Degeneration
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Phase 3 Macular Degeneration Trial, Recruiting

NCT07440225
Recruiting Phase 3 🇦🇺 Australian site

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have a specific type of eye condition called choroidal neovascularization (abnormal blood vessel growth at the back of the eye) caused by age-related macular degeneration, including certain related conditions affecting the retina, in at least one eye — and who have not yet received any treatment for it
  • People whose diagnosis of this wet form of age-related macular degeneration was confirmed within the last 21 days before starting the study treatment

Who may not be able to join:

  • People with high blood pressure that is not under control at the time of their screening appointment
  • People who have had laser treatment on the macula (a part of the retina) in the eye being studied
  • People who have a history of eye inflammation (uveitis) in either eye
  • People who have had cataract surgery, a certain type of glaucoma surgery, or a specific laser eye procedure (YAG laser capsulotomy) in the eye being studied within the past 90 days
  • People with glaucoma (a condition causing pressure in the eye) that is not under control in the eye being studied
  • People who have another active retinal condition in the eye being studied, beyond the condition this trial is looking at
  • People who have previously received injections into the eye (such as anti-VEGF therapy or any other intravitreal treatment) in the eye being studied

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Medical Director, Merck Sharp & Dohme LLC

Phone: 1-888-577-8839

Australian sites

Eye Clinic Albury Wodonga (Site 425), Albury,
+61 2 9959 0053
Marsden Eye Specialists (Site 420), Parramatta,
+ 61 2 9635 7077
Marsden Eye Specialists (Site 423), Strathfield,
+61 2 9746 2988
Sydney Eye Hospital (Site 426), Sydney,
+61 2 9382 7379
Sydney Retina Clinic and Day Surgery (Site 424), Sydney,
+61 2 9570 1522

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Sponsor
EyeBiotech Ltd.
Registry
ClinicalTrials.gov
Start date
27 March 2026
Est. completion
30 June 2028

Where this trial is recruiting

🇦🇷 Argentina 🇦🇺 Australia 🇮🇱 Israel 🇱🇻 Latvia 🇪🇸 Spain 🇨🇭 Switzerland 🇬🇧 United Kingdom 🇺🇸 United States

5 site(s) in Australia. Confirm current status and contact details directly with the trial site.

Primary endpoints

Mean Change in Best-Corrected Visual Acuity (BCVA) [Early Treatment of Diabetic Retinopathy Study (ETDRS Letters)] From Baseline to Year 1

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov