Phase 2 Macular Degeneration Trial, Recruiting NCT07441642 Sponsor: Novartis Pharmaceuticals Condition: Macular Degeneration
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Phase 2 Macular Degeneration Trial, Recruiting

NCT07441642
Recruiting Phase 2 🇦🇺 Australian site

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 50 or older, of any gender.
  • People who have been diagnosed with geographic atrophy (a type of vision loss) caused by age-related macular degeneration (AMD) in at least one eye, where the affected area is within a specific size range — not too small and not too large (confirm with trial site for exact measurements).
  • If the area of vision loss is made up of multiple patches, at least one patch must meet a minimum size requirement, and the total affected area must still fall within the specified range (confirm with trial site).
  • The entire affected area in the eye being studied must be fully visible within a standard eye imaging scan and must not extend into a specific nearby region of the retina (confirm with trial site).
  • People whose vision in the study eye is at a level of at least 20/200 on a standard eye chart test.

Who may not be able to join:

  • People who have a history of, or currently show signs of, a condition involving abnormal blood vessel growth under the retina (sometimes called "wet" AMD) in either eye, based on imaging reviewed at screening.
  • People who have previously received any cell or gene therapy treatment in either eye.
  • People whose macular vision loss is caused by a condition other than AMD, such as certain inherited or drug-related eye diseases.
  • People who have had eye surgery (including cataract or retinal surgery) in the study eye within the 3 months before the trial's starting point.
  • People who have clouding of the eye, uncontrolled eye movements, severely drooping eyelids, restricted eye movement, or head tremor that could interfere with eye imaging quality, as assessed by the treating doctor.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: 1-888-669-6682

Australian sites

Novartis Investigative Site, Albury, New South Wales
Novartis Investigative Site, Parramatta, New South Wales
Novartis Investigative Site, Strathfield, New South Wales
Novartis Investigative Site, East Melbourne, Victoria

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Registry
ClinicalTrials.gov
Start date
9 March 2026
Est. completion
21 August 2029

Where this trial is recruiting

🇦🇺 Australia 🇧🇬 Bulgaria 🇨🇦 Canada 🇨🇿 Czechia 🇫🇷 France 🇩🇪 Germany 🇭🇺 Hungary 🇮🇹 Italy 🇯🇵 Japan 🇵🇱 Poland Puerto Rico 🇷🇴 Romania 🇪🇸 Spain 🇬🇧 United Kingdom 🇺🇸 United States

4 site(s) in Australia. Confirm current status and contact details directly with the trial site.

Primary endpoints

Change of geographic atrophy (GA) lesion area

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov