Phase 2 Breast Cancer Trial, Recruiting NCT07443943 Sponsor: University of Michigan Rogel Cancer Center Condition: Breast Cancer
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Phase 2 Breast Cancer Trial, Recruiting

NCT07443943
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are planning to start a standard aromatase inhibitor (AI) medication and expected to take it for at least 24 weeks, either for stage 0–3 breast cancer or to reduce the risk of developing breast cancer
  • People who are also taking certain other medications alongside AI therapy — including GnRHa (a hormone-related treatment), bone-protecting medications, anti-HER2 therapy, ribociclib, or PARP inhibitors — may still be eligible
  • People whose average joint pain over the past 7 days has been rated between 0 and 6 on a scale of 0 to 10
  • People who are able to swallow and take oral (by mouth) medication
  • People who are able to read and understand English
  • People who are aware of their diagnosis, understand what the study involves, and are able to sign a consent form

Who may not be able to join:

  • People whose breast cancer has spread to distant parts of the body (metastatic breast cancer)
  • People who are currently taking or planning to take abemaciclib (a cancer medication) during the study period
  • People who are currently receiving or planning to receive chemotherapy or immunotherapy during the study period
  • People who are pregnant, breastfeeding, or planning to become pregnant during the study period
  • People with a known active inflammatory bowel disease
  • People who have had a colectomy (surgical removal of part or all of the colon) or gastric bypass surgery
  • People who have previously taken AI therapy, except if it was used as part of fertility treatment
  • People who are planning to use prebiotic supplements during the study period
  • People who are using estrogen supplements (other than vaginal estrogen products)
  • People who are currently participating in another clinical trial involving an investigational (unapproved) treatment

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Norah L Henry, M.D., University of Michigan Rogel Cancer Center

Phone: 1-800-865-1125

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
University of Michigan Rogel Cancer Center
Registry
ClinicalTrials.gov
Start date
22 April 2026
Est. completion
1 September 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Proportion of patients who took at least 70% of resistant potato starch (RPS) doses per protocol

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov