Phase 2 Schizophrenia Trial, Recruiting NCT07459660 Sponsor: MapLight Therapeutics Condition: Schizophrenia
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Phase 2 Schizophrenia Trial, Recruiting

NCT07459660
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are willing and able to sign a consent form agreeing to take part, or if you are not able to do this yourself, a trusted legal representative can sign on your behalf and you can show your agreement in another way.
  • You have already completed the full double-blind treatment period of a specific earlier study involving the drug ML-007C-MA (study ML-007C-MA-221).
  • The doctor running the trial believes you could benefit from continuing to take the study drug ML-007C-MA over a longer period of time.
  • You have a designated care partner (such as a family member or caregiver) who sees or speaks with you often enough to accurately report on your symptoms and whether you are taking the study drug as directed.
  • You live in a stable home setting — such as your own home, an assisted living facility, or a nursing home — and are expected to stay in that same setting for the whole duration of the study.

Who may not be able to join:

  • You are currently receiving hospice care, are confined to bed, or are receiving end-of-life care.
  • You need to take certain medications that are not allowed under this trial's rules.
  • You have developed a new or worsening health condition during or since the earlier study that, in the doctor's opinion, could put you at risk, affect your ability to follow the study procedures, or affect how results are measured.
  • You have had a significant abnormal result from a physical exam, vital signs check, heart test (ECG), or blood/lab test during or since the earlier study that could affect your safety or the study results (confirm with trial site).
  • You have developed an allergy or bad reaction to the study drug ML-007C-MA or any of its ingredients since taking part in the earlier study.
  • You are considered to be at an elevated risk of suicidal thoughts or behaviour.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: MapLight Therapeutics, MapLight Therapeutics

Phone: +1 650 839 4380

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
MapLight Therapeutics
Registry
ClinicalTrials.gov
Start date
25 March 2026
Est. completion
1 March 2029

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

To assess the safety and tolerability of long-term ML-007C-MA administration in participants with hallucinations and delusions associated with AD

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov