Osteoarthritis Trial, Recruiting NCT07464080 Sponsor: Ottawa Hospital Research Institute Condition: Osteoarthritis
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Osteoarthritis Trial, Recruiting

NCT07464080
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are a man or woman aged 18 years or older
  • You are having a total knee replacement for the first time (not a repeat procedure)
  • You have been diagnosed with osteoarthritis, inflammatory arthritis (such as rheumatoid arthritis), or a condition where bone tissue in the knee has died due to lack of blood supply

Who may not be able to join:

  • You are unable or unwilling to sign a consent form agreeing to take part in the study
  • You do not speak English or French, and there is no qualified translator, family member, or someone who can make decisions on your behalf available to help
  • You have a history of serious neurological conditions, such as a significant brain injury, epilepsy, or multiple sclerosis
  • You have been diagnosed with cognitive impairment or dementia
  • You are having a repeat knee replacement surgery or are having both knees replaced at the same time
  • You regularly use opioid pain medications on an ongoing, long-term basis

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 15 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Simon Garceau, The Ottawa Hospital

Phone: 613-737-8899

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Ottawa Hospital Research Institute
Registry
ClinicalTrials.gov
Start date
1 April 2026
Est. completion
31 December 2027

Where this trial is recruiting

🇨🇦 Canada

Primary endpoints

Preoperative Resting-State fMRI Brain connectivity as a Predictor of Patient operative Satisfaction after Total Knee Arthroplasty measured by Patient-Reported Outcomes Measurement Information System (PROMIS ); Preoperative Resting-State fMRI Brain connectivity as a Predictor of Patient operative Satisfaction after Total Knee Arthroplasty measured by Oxford Knee Score (OKS)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 15 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov