Osteoarthritis Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• Adults aged 18 or older who have been diagnosed with moderate to severe knee osteoarthritis (grade 3 or 4 on a standard medical scale) and report a pain level of 5 or higher out of 10.
• People whose leg alignment shows an inward bowing of the knee beyond a certain angle (sometimes called "varus" or "bow-legged" alignment), as measured by their doctor.
• People whose overall health means they can safely undergo anaesthesia, up to a moderate risk level on a standard medical scale (ASA grade III or below).
• People with a body mass index (BMI) below 35 kg/m².
• People who are able to attend all follow-up appointments over the full 12-month study period.
• People who are mentally able to understand and follow the study requirements.
• People who are willing to provide written consent to take part in the study.

Who may not be able to join:

• People with a BMI above 40 kg/m².
• People whose knee ligaments are unstable in a way that would require additional ligament support devices, or who have significant bone loss in the knee area.
• People who have difficulty bearing weight on their other (opposite) leg.
• People who have metal implants or foreign objects in either of their lower limbs.
• People who have previously had knee surgery such as ligament reconstruction or bone-correction surgery on the thigh or shin bone.
• People who do not wish to take part in the study.
• People who are unlikely to follow their treating doctor's instructions or the required study schedule.

Important: Always verify eligibility with the trial site directly before applying.