Peripheral Arterial Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- Adults aged 18 or older (male or female)
- People who have been diagnosed with peripheral artery disease (a condition where narrowed arteries reduce blood flow to the limbs) and have symptoms, which may include one or more of the following:
- People who experience leg pain or cramping when walking (called intermittent claudication), where blood flow measurements or imaging show significant artery narrowing, AND who also have at least one of: atherosclerosis (artery disease) in more than one part of the body, diabetes, heart failure, or reduced kidney function
- People who have pain in their legs or feet even at rest, or have tissue death or gangrene in a limb due to poor blood flow
- People who have had a procedure to restore blood flow to a limb (such as bypass surgery or a procedure to open a blocked artery), or who have had a leg or foot amputation due to artery disease
- People who are able to give written or verbal consent to participate
Who may not be able to join:
- People who have a medical reason why they cannot take colchicine or iodinated contrast (a dye used in medical imaging)
- People who already need to take colchicine long-term for another medical condition
- People who are currently experiencing ongoing diarrhoea
- People who have had a procedure to restore blood flow to a limb within the past 6 weeks
- People with severely reduced kidney function (confirm with trial site for specific measurement details)
- People with cirrhosis or severe long-term liver disease
- Women who are currently pregnant or breastfeeding
- Women who could become pregnant and are not using reliable contraception, or who are planning to become pregnant during the study period
- People who currently use or plan to use long-term certain medications, including cyclosporine, verapamil, some HIV medications, certain antifungal medicines, or certain antibiotic medicines (confirm with trial site for the full list)
- People who are unlikely to be able to attend follow-up appointments
- People whose life expectancy is less than one year
- People who are unable or unwilling to give informed consent
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Rachael O Forsythe, MBChB, PhD, FRCS (Vascular), University of Edinburgh
Phone: +447495905258
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Quantification of PET tracer uptake of [68Ga]DOTATATE, [18F]GP1 and [18F]NaF in the symptomatic lower limb(s)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 20 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.