Asthma Trial, Recruiting NCT07486401 Sponsor: National Healthcare Group Polyclinics Condition: Asthma
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Asthma Trial, Recruiting

NCT07486401
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are Singaporean citizens or Singapore Permanent Residents
  • People aged 21 to 65 years old
  • People who have been diagnosed with asthma by a doctor for at least 4 weeks
  • People who are on, or are about to start, a mild-to-moderate level of asthma treatment (known as GINA 2025 steps 1 to 3) (confirm with trial site)
  • People who have not had a serious worsening of asthma symptoms in the 4 weeks before joining the trial (a serious worsening means needing steroid tablets or injections for 3 or more days, a visit to the emergency department, or a hospital stay)
  • People who are able and willing to attend check-up appointments roughly every 4 months over a 1-year period
  • People who are able to give informed consent to participate
  • People who have a stable heart and blood pressure condition, meaning no active heart disease or irregular heartbeat symptoms, and any high blood pressure is well controlled

Who may not be able to join:

  • People who have had life-threatening asthma in the past that required a breathing tube or a stay in an intensive care unit
  • People with severe asthma or asthma that has been difficult to treat
  • People currently taking long-term immune-suppressing medications, the medication Montelukast (a leukotriene receptor antagonist), Theophylline, or long-term steroid tablets
  • People who have a known condition other than asthma that causes high levels of a certain type of white blood cell called eosinophils (for example, a parasitic infection), as determined by the treating doctor
  • People currently using beta-blocker medications, including beta-blocker eye drops
  • People who have used steroid tablets, suppositories, or injections in the 30 days before joining, or a long-acting steroid injection in the 12 weeks before joining
  • People who have a diagnosed lung condition other than asthma, such as Chronic Obstructive Pulmonary Disease (COPD), scarring of the lungs (interstitial lung disease), or bronchiectasis
  • People who have another significant illness or condition — affecting the heart, digestive system, liver, kidneys, nervous system, muscles or joints, hormones, mental health, or other areas — that the trial doctor believes could affect safety or the trial's results (confirm with trial site)
  • People who are currently taking part in another clinical trial for asthma
  • People who are pregnant or planning to become pregnant during the study period
  • People who plan to travel outside of Singapore for 16 or more consecutive weeks during the study
  • People whom the trial doctor assesses as unlikely to be able to follow study instructions or complete study procedures

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 16 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: (65) 6355 3000

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
National Healthcare Group Polyclinics
Registry
ClinicalTrials.gov
Start date
3 December 2025
Est. completion
31 December 2028

Where this trial is recruiting

🇸🇬 Singapore

Primary endpoints

Time to first asthma exacerbation requiring hospitalisation; Number of asthma exacerbations not requiring hospitalisation; Worsening of asthma symptoms

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 16 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov