Phase 3 Lymphoma Trial, Recruiting NCT07493109 Sponsor: Ou Bai, MD/PHD Condition: Lymphoma
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Phase 3 Lymphoma Trial, Recruiting

NCT07493109
Recruiting Phase 3

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 18 to 80 years old, of any sex
  • People who have not previously received treatment for their DLBCL (such as chemotherapy, targeted therapy, immunotherapy, or surgery aimed at the lymphoma), and who have achieved a complete response (meaning no detectable cancer) after 6 cycles of a standard chemotherapy combination called R-CHOP, confirmed by scans and other assessments
  • People diagnosed with a specific type of blood cancer called Diffuse Large B-Cell Lymphoma (DLBCL) that tests positive for a protein called CD20, and who also have evidence of active or chronic hepatitis B virus (HBV) infection — people already on stable hepatitis B antiviral medication for at least 4 weeks before joining may also be considered
  • People with a general health and activity level rated as 0, 1, or 2 on a standard medical scale (meaning broadly independent and able to carry out daily activities, with or without some limitations)
  • People whose blood test results at screening meet certain minimum thresholds for red blood cells, white blood cells, platelets, kidney function, and liver function (confirm with trial site for specific values)
  • People whose doctor estimates they have a life expectancy of at least 6 months
  • People who are able to understand and willingly sign a consent form for the trial

Who may not be able to join:

  • People who are pregnant, breastfeeding, or who are able to have children but are unwilling to use contraception
  • People with a history of certain significant heart conditions, including irregular heart rhythms, heart attack within the past year, heart failure, or symptomatic coronary artery disease requiring medication
  • People who have previously had an organ transplant
  • People who received treatment for low blood cell counts (as a symptom-relief measure) within the 7 days before joining the trial
  • People with active (ongoing) bleeding
  • People with a history of, or current diagnosis of, blood clots, stroke, or related conditions
  • People with an active infection, or who have had a persistent fever in the 14 days before joining the trial
  • People who have not yet fully recovered (at least 6 weeks) from a major surgical procedure
  • People with significantly abnormal liver or kidney function test results
  • People with a mental health condition that would prevent them from giving informed consent
  • People with a drug or alcohol dependency that could interfere with the trial results
  • People whose lymphoma has spread to the brain or central nervous system
  • People whom the trial doctor considers unsuitable for the study for any other reason

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 7 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Ou Bai, PHD, The First Bethune Hospital of Jilin University

Phone: 15804302602

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Sponsor
Ou Bai, MD/PHD
Registry
ClinicalTrials.gov
Start date
30 May 2026
Est. completion
30 September 2029

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Progression-free survival (PFS)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 7 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov