Early Phase 1 Peripheral Arterial Disease Trial, Recruiting NCT07493447 Sponsor: Eben Rosenthal Condition: Peripheral Arterial Disease
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Early Phase 1 Peripheral Arterial Disease Trial, Recruiting

NCT07493447
Recruiting Early Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have a brain lesion (an abnormal area in the brain) and are already scheduled to have it surgically removed as part of their normal medical care — this includes people who have previously had chemotherapy, radiation, or a biopsy to diagnose their condition.
  • People aged 18 years or older.
  • People whose blood tests and organ function results (including kidney, liver, and blood counts) are considered acceptable for surgery and for receiving the study drug — these tests must have been done within 30 days before starting the study treatment.
  • Women who could become pregnant must have a negative pregnancy test within 7 days before receiving the study drug.
  • People who are able to understand and sign a consent form, or who have a healthcare decision-maker who can sign on their behalf.

Who may not be able to join:

  • People who have had a heart attack, stroke, or uncontrolled heart failure within the 6 months before joining the trial.
  • People who have previously had a serious reaction to a monoclonal antibody treatment (a type of targeted therapy drug).
  • People who are currently pregnant or breastfeeding.
  • People whose heart electrical activity test (ECG) shows a specific irregular reading above a certain threshold (confirm with trial site).
  • People who have low magnesium or phosphorus levels in their blood and are experiencing symptoms related to this.
  • People who are currently taking certain heart rhythm medications, specifically those known as Class IA drugs (such as quinidine or procainamide) or Class III drugs (such as amiodarone, dofetilide, or sotalol).
  • People who have a history of, or signs of, scarring or inflammation in their lungs (such as interstitial pneumonitis or pulmonary fibrosis).
  • People who have severe kidney disease or produce no urine.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 22 July 2026
Early Phase 1 studies are small, early exploratory studies that come before the main Phase 1 to 3 testing, so a standard phase success rate does not apply.

Contact this trial

Principal Investigator: Peter Morone, MD, Vanderbilt University Medical Center

Phone: 615-421-4370

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Early Phase 1
Sponsor
Eben Rosenthal
Registry
ClinicalTrials.gov
Start date
1 July 2026
Est. completion
1 May 2030

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Determine the safety of panitumumab-IRDye800 as an imaging agent in patients undergoing surgery for intracranial lesions.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov