Phase 3 Macular Degeneration Trial, Recruiting NCT07496567 Sponsor: EyeBiotech Ltd. Condition: Macular Degeneration
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Phase 3 Macular Degeneration Trial, Recruiting

NCT07496567
Recruiting Phase 3

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have a specific type of eye condition called choroidal neovascularization (abnormal blood vessel growth at the back of the eye) caused by age-related macular degeneration, which has not been treated before, in at least one eye (confirm with trial site for exact lesion types)
  • People whose diagnosis of this wet form of age-related macular degeneration was made within the last 21 days before starting the study treatment

Who may not be able to join:

  • People who have high blood pressure that is not well controlled at the time of screening
  • People who have previously had laser treatment on the central part of the retina (macular laser photocoagulation) in the eye being studied
  • People who have a history of uveitis (inflammation inside the eye) in either eye
  • People who have had cataract surgery, a certain type of glaucoma surgery, or a specific laser eye procedure (YAG laser capsulotomy) in the study eye within the past 90 days
  • People who have glaucoma (a pressure-related eye condition) in the study eye that is not well controlled
  • People who have another active retinal disease in the study eye, beyond the condition this trial is investigating
  • People who have previously received injections into the eye (such as anti-VEGF therapy or other intravitreal treatments) in the study eye

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 22 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Medical Director, Merck Sharp & Dohme LLC

Phone: 1-888-577-8839

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Sponsor
EyeBiotech Ltd.
Registry
ClinicalTrials.gov
Start date
15 April 2026
Est. completion
31 July 2028

Where this trial is recruiting

🇧🇷 Brazil 🇨🇴 Colombia 🇨🇿 Czechia 🇫🇷 France 🇺🇸 United States

Primary endpoints

Mean Change in Best-Corrected Visual Acuity (BCVA) [Early Treatment of Diabetic Retinopathy Study (ETDRS Letters)] From Baseline to Year 1

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov