Stroke Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People aged 18 or older
• People who have had an acute ischemic stroke (a stroke caused by a blocked blood vessel) affecting a major artery at the front of the brain, confirmed by a scan (CTA, MRA, or DSA)
• People whose stroke severity score (NIHSS) was 6 or higher before their procedure
• People who were largely independent before this stroke, with little to no disability (Modified Rankin Scale score of 1 or less)
• People who have already received an endovascular treatment (a procedure to unblock the artery) within 24 hours of their stroke, and where that treatment successfully restored blood flow to a satisfactory level
• People whose brain scan shows limited damage (ASPECTS score of 3 or higher); for strokes that began between 6 and 24 hours before treatment, the person must also be aged 80 or under
• Cases where the patient or their legally authorised representative has signed the consent form

Who may not be able to join:

• People whose scans show a stroke affecting more than one blood vessel territory in the brain at the same time
• People whose scans show a torn or split artery (arterial dissection)
• People who had any bleeding in the brain before the unblocking procedure
• People with known allergies or intolerances to blood-thinning medications, iodine-based contrast dye, or anaesthetics
• People with a serious active infection (such as sepsis) or failure of multiple organs
• People with a known bleeding disorder or clotting deficiency, or whose blood-thinning medication levels are outside the accepted range (confirm specific thresholds with trial site)
• People with a very low platelet count (below 50 × 10⁹/L) — platelets are cells that help blood clot
• People whose blood sugar level is either very low or very high at the time of the stroke
• People with very high blood pressure that cannot be brought under control with medication
• People with severe heart failure, a recent heart attack, or unstable chest pain
• People with untreated moderate or severe narrowing of the heart's arteries, or who have previously had coronary artery bypass surgery
• People currently receiving kidney dialysis, or with severely reduced kidney function
• People with a known brain aneurysm (a bulge in a blood vessel) or an abnormal tangle of blood vessels in the brain
• People with a malignant brain tumour or an active infection of the brain or nervous system
• People with a pre-existing neurological or psychiatric condition (such as dementia) that would affect the ability to assess stroke recovery
• People who are pregnant or breastfeeding at the time of admission
• People whose life expectancy is estimated to be less than 6 months
• People currently taking part in another clinical trial involving an investigational drug or device
• People with skin damage or other conditions that would prevent medical patches or electrodes from being applied to the skin
• People with severe agitation or other conditions that would interfere with data collection

Important: Always verify eligibility with the trial site directly before applying.