Breast Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who are willing and able to give their consent to take part in the study
• People who are 18 years of age or older at the time they give consent
• People whose overall physical functioning is rated at a certain level by their doctor (a score of 2 or lower on a standard cancer patient health scale — confirm with trial site)
• People who have gone through menopause at the time they join the study
• People diagnosed with Stage I or II breast cancer (early-stage, not spread to distant parts of the body)
• People who are planned to have breast surgery (either full or partial breast removal) as their first treatment, without needing any chemotherapy, hormone therapy, or other systemic treatment before surgery
• People who have tissue available from their initial breast biopsy, taken as part of their standard care
• People who, in the opinion of the study doctor, are able to follow a ketogenic (very low carbohydrate, high fat) diet and meet study requirements such as attending video appointments, using apps on a smartphone, measuring blood sugar and ketone levels at home, keeping a food and exercise diary, and preparing meals that fit the ketogenic diet

Who may not be able to join:

• People whose doctors have determined they need treatment (such as chemotherapy or hormone therapy) before surgery
• People whose breast surgery is planned to happen in less than 3 weeks from when they would join the study
• People who are unable to follow a ketogenic diet
• People who have been consistently following a ketogenic diet in the past 3 months
• People who are already taking part in another structured diet program during the study period
• People whose breast cancer is a type that does not start in the breast tissue lining, such as sarcoma or lymphoma
• People with a Body Mass Index (a measure of body weight relative to height) below 18.5 (considered underweight)
• People with other health conditions that, in the study doctor's opinion, would prevent them from safely taking part
• People with Type 1 diabetes
• People who use insulin or other diabetes medications taken by mouth to manage blood sugar
• People who have experienced any of the following in the past 6 months: a heart attack, unstable chest pain (angina), a dangerous heart rhythm problem, severe sudden heart failure, a stroke, or a life-threatening spike in blood pressure
• People with high blood pressure that remains uncontrolled even with blood pressure medication
• People with end-stage kidney, liver, or heart disease
• People with inherited genetic conditions that affect how the body processes fats (such as certain enzyme deficiencies — confirm specific conditions with trial site)
• People with a condition called G6PD deficiency, which affects red blood cells
• People with conditions that affect how the body absorbs food, such as inflammatory bowel disease, a history of gastric sleeve surgery, or prior bowel removal surgery
• People with a history of recurring kidney stones or a known predisposition to developing them
• People with very high triglyceride (blood fat) levels of 500 or above
• People with known mental health or substance use conditions that would interfere with taking part in the study

Important: Always verify eligibility with the trial site directly before applying.