Pulmonary Hypertension Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who have been diagnosed with COPD, confirmed by a specific breathing test result (where the FEV1/FVC ratio is less than 0.7)
- People who are 40 years of age or older
Who may not be able to join:
- People who had a COPD flare-up or worsening episode in the 3 months before enrolling
- People whose COPD medications were changed in the 3 weeks before enrolling
- People who need more than 6 litres per minute of supplemental oxygen while at rest
- People who need more than 10 litres per minute of supplemental oxygen during physical activity
- People with active or poorly controlled heart conditions, such as: high blood pressure above 150/100 even with medication, chest pain from coronary artery disease, weak heart pumping function, uncontrolled irregular heartbeat, more than mild heart valve problems, or more than moderate leaking of the tricuspid heart valve
- People with signs of fluid build-up in the body, such as swelling in the neck veins or more than slight swelling in the legs or feet
- People who are classified as World Health Organization Functional Class IV, meaning their symptoms are severely limiting even at rest (confirm with trial site)
- People with known pulmonary hypertension (high blood pressure in the lungs) where the average pressure in the main lung artery is above 45 mmHg
- People with untreated severe sleep apnoea and/or a condition where obesity affects breathing during sleep
- People with an active cancer (other than skin cancer)
- People with physical conditions that would prevent them from exercising on an upright stationary bike, such as severe joint problems or balance and walking difficulties
- People who are pregnant
- People whose body mass index (a measure of weight relative to height) is below 18 or above 35
- People whose blood thickness level (haematocrit) is below 25% or above 55%
- For the group having a right heart catheterisation (a procedure to measure pressures in the heart): people who take blood thinners that cannot be safely stopped for the study visit
- For the group having a right heart catheterisation or exercise training: people whose breathing test shows lung function below 20% of expected
- For the exercise training part: people who are already doing regular exercise training (more than 30 minutes at a moderate intensity, 3 or more times per week)
- For the exercise training part: people who are unable to attend in-person exercise sessions of approximately 35 minutes, 3 times per week, for 3 weeks at the start of the program
- For the hybrid remote exercise training option: people with any health conditions that would make exercising at home unsafe, such as balance or walking difficulties
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Lindsay Forbes, MD, University of Colorado, Denver
Phone: (303)724-4020
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Right ventricular contractility measured by transthoracic echocardiography
Can't join this trial?
Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.