Macular Degeneration Trial, Recruiting NCT07582042 Sponsor: University of Utah Condition: Macular Degeneration
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Macular Degeneration Trial, Recruiting

NCT07582042
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are between 65 and 90 years old
  • You have been diagnosed with Geographic Atrophy (a type of advanced dry age-related macular degeneration, which causes vision loss) in at least one eye
  • The affected area in your eye is a specific size — not too small and not too large (confirm with trial site)
  • The damaged area in your eye is positioned away from the edges of certain eye scan images (confirm with trial site)
  • The damaged area has not spread into a specific region near the optic nerve at the back of your eye (confirm with trial site)
  • You are already receiving a treatment called pegcetacoplan (also known as Syfovre) by injection into the eye, and have had at least one injection before joining the study
  • Your vision, even with glasses or contact lenses, falls within a certain range — from roughly normal to moderately reduced (confirm with trial site)
  • You are able to take part in a special vision sensitivity test and eye imaging required by the study
  • You are willing and able to give your informed consent to take part

Who may not be able to join:

  • You have had or currently have a "wet" form of macular degeneration (where abnormal blood vessels leak fluid) in the eye being studied
  • You have a very strong glasses prescription or significant astigmatism (a common focusing problem with the eye)
  • You have other eye conditions that could affect the study results, such as diabetic eye disease with swelling, a blocked vein in the eye, an inherited eye condition, or poorly controlled glaucoma
  • You have cloudiness or blockages in your eye (such as a dense cataract, corneal scarring, or bleeding in the eye) that would prevent clear eye testing or imaging
  • You have a serious health condition that the medical team believes could affect your ability to fully take part in, or complete, the trial (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Monika Fleckenstein, MD, University of Utah, Department of Ophthalmology

Phone: +1

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
15 June 2026
Est. completion
1 May 2029

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Slope of mesopic retinal sensitivity decline (dB/year) at predefined distances from the Geographic Atrophy (GA) border.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov