Phase 1 Lymphoma Trial, Recruiting NCT07586618 Sponsor: Allterum Therapeutics, Inc Condition: Lymphoma
Back to Lymphoma

Phase 1 Lymphoma Trial, Recruiting

NCT07586618
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with a specific type of blood cancer called T/B-ALL or T/B-LL (types of leukemia or lymphoma affecting white blood cells)
  • People whose cancer has come back after treatment or has not responded to treatment, and where no other curative treatment options are available
  • People whose major organs (such as heart, liver, and kidneys) are functioning well enough, and who are in a sufficient overall state of health (confirm specific requirements with trial site)

Who may not be able to join:

  • People whose cancer has spread to the central nervous system (the brain and spinal cord) at a level classified as "CNS3" (confirm with trial site)
  • People who have certain inherited conditions that affect how the body repairs DNA, such as Fanconi anaemia or Bloom syndrome, or people who have Down Syndrome (trisomy 21)
  • People who have previously received a treatment that targets a protein called CD127
  • People who have an infection that is not currently under control

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Eric Schafer, MD, Baylor College of Medicine

Phone: 15153439875

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Sponsor
Allterum Therapeutics, Inc
Registry
ClinicalTrials.gov
Start date
1 June 2026
Est. completion
1 May 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Incidence of Treatment-Emergent Adverse Events (TEAEs) at each dose level; Determine the Recommended Phase 2 Dose (RP2D)/ Recommended Dose for Expansion (RDE) of 4A10 as a single agent in patients with R/R ALL/LL.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov