Phase 2 Ovarian Cancer Trial, Recruiting NCT07589543 Sponsor: Beijing Biotech Condition: Ovarian Cancer
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Phase 2 Ovarian Cancer Trial, Recruiting

NCT07589543
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 18 to 75 who are able to give written consent to participate
  • People who have been diagnosed (confirmed by tissue testing) with ovarian cancer, fallopian tube cancer, or primary peritoneal cancer that has come back or stopped responding to standard treatment, and who have already received at least 2 prior treatment regimens
  • People whose cancer can be measured on scans (per standard research criteria) and who are generally well enough to carry out light activity or normal daily tasks
  • People who have a tumour tissue sample available for testing, and whose tumour shows enough of the specific targets the trial is studying (the trial team will assess this using a laboratory test on the tissue sample)
  • People with healthy enough kidney, liver, blood, and organ function as defined by the trial, and who have a negative pregnancy test and agree to use effective contraception for a period defined by the trial after receiving the treatment

Who may not be able to join:

  • People with active cancer spread to the brain or the lining around the brain, unless it has been treated and has been stable for a period defined by the trial
  • People who have previously received a gene-modified cell therapy targeting any of the specific proteins this trial studies (GD2, MUC1, PSMA, or mesothelin) within the last 6 months
  • People with an active, uncontrolled infection, including uncontrolled HIV, hepatitis B, hepatitis C, or an active systemic fungal infection
  • People with serious heart conditions, such as a recent heart attack, unstable chest pain, an uncontrolled irregular heartbeat, or a heart pumping function below 50%
  • People with an active autoimmune disease that required immune-suppressing medication in the 14 days before the trial's preparatory treatment phase (routine low-dose steroid replacement may be permitted — confirm with trial site)
  • People who have previously had an organ transplant or a bone marrow/stem cell transplant from another person
  • People who are pregnant or breastfeeding
  • People whose overall health or circumstances, in the treating doctor's judgement, could put them at risk or affect their ability to safely take part

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 6 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: +86 13076790030

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Beijing Biotech
Registry
ClinicalTrials.gov
Start date
2 March 2026
Est. completion
14 March 2027

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Incidence of dose-limiting toxicities (DLTs) to determine maximum tolerated dose (MTD); Incidence, severity, and relatedness of adverse events (AEs)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 6 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov