Phase 2 Alzheimer's Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You have been experiencing a slow, gradual decline in memory or thinking that has been going on for 6 months or longer.
- You show at least one key sign or symptom commonly associated with dementia with Lewy bodies (DLB) (confirm with trial site for which symptoms qualify).
- You score 20 or higher on a standard memory and thinking test called the MoCA (Montreal Cognitive Assessment).
- A blood test result meets specific protein levels related to this study (confirm with trial site).
- A sample of fluid taken from around your spine shows signs of a certain type of brain protein buildup linked to this condition.
- The same spine fluid sample also shows signs of another specific protein linked to this condition.
- You have at least one trusted person in your life (such as a family member or close friend) who knows you well, sees you regularly, is familiar with your daily activities and thinking abilities, and is willing to take part in the study.
Who may not be able to join:
- You have another serious or unstable health condition that could interfere with the study.
- You have, or are suspected to have, another significant brain or nervous system condition (other than the one being studied) that could affect your thinking or ability to complete the trial.
- You have a history of cancer that the study doctor believes has a high chance of coming back during the study period.
- You have a history of severe allergic reactions to medications or treatments.
- You have previously received any treatment specifically targeting amyloid (a protein linked to brain disease).
- You are currently receiving a vaccine or active immunization targeting amyloid-beta.
- Your brain MRI scan, as reviewed by the study team, does not meet the requirements to enter the study.
- You are unable to have an MRI or PET scan for any reason (for example, due to a pacemaker or severe claustrophobia).
- You are unable to have a lumbar puncture (spinal tap) for any medical reason.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 8 AM - 8 PM Eastern time (UTC/GMT - 5 hours, EST), Eli Lilly and Company
Phone: 1-317-615-4559
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Change from Baseline on Clinical Dementia Rating - Sum of Boxes (CDR-SB)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 20 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.