Phase 1 Prostate Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have been diagnosed with prostate cancer and fall into one of these groups: cancer that is suspected to have spread and are being considered for initial treatment; rising PSA levels suggesting the cancer may have returned (confirmed PSA level above 0.2 ng/mL); or metastatic disease where treatment with a specific type of targeted radiation therapy (lutetium-177 PSMA) is being considered — including those with negative or unclear PSMA scan results, as long as prostate cancer has been confirmed by a tissue biopsy
• People who are biologically capable of fathering children must agree to use effective contraception for three months from the time the study drug is given
• People aged 18 or older
• People who are generally well enough to carry out all normal daily activities, or whose illness causes only minor limitations (this is measured by a standard medical scale — confirm with trial site)
• People who have no current infections or other active illnesses at the time of joining
• People whose side effects from any previous treatment (such as surgery, radiation, or chemotherapy) have largely resolved — with the exception of hair loss and tiredness, which are allowed
• People with a life expectancy of more than 12 weeks
• People who are able to undergo the imaging procedures required by the study
• People who have read and signed a dated consent form confirming they have been fully informed about the study
• People who are willing and able to attend all required visits and follow all study procedures

Who may not be able to join:

• People with chronically reduced kidney function, based on specific blood or urine test results (confirm with trial site)
• People with an active hepatitis infection
• People with significant heart problems, such as severe heart failure, a heart attack within the past year, uncontrolled high blood pressure, or irregular heart rhythms
• People with any other ongoing condition that the study investigators believe could make participation unsafe or affect how well the study can be carried out
• People who have had a major surgical procedure (such as abdominal, heart, or chest surgery) within 4 weeks before receiving the study drug — note that minor procedures such as biopsies are not considered a reason for exclusion
• People with a serious wound, ulcer, or bone fracture that has not healed
• People with a known allergy to the study medication or any of its ingredients
• People who have received any cancer treatment (such as chemotherapy, immunotherapy, radiation, or surgery) within 3 weeks before the study scan
• People who have received, or are due to receive, another experimental medication from one month before the study injection through to the end of study participation

Important: Always verify eligibility with the trial site directly before applying.