Phase 3 Alzheimer's Disease Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You must have already completed a specific earlier part of this research study (called "AACM Addendum 7").
• You must have a reliable person (and a backup person) who knows you well and can speak to your daily activities, behavior, and thinking abilities.
• You must have been assigned female at birth and no longer be able to become pregnant, or have been assigned male at birth.
• You must be willing to follow local rules about contraception (birth control) during the study, if required.

Who may not be able to join:

• You have a serious or unstable health condition that the study doctor believes could affect your ability to take part.
• You are unable to have an MRI scan — for example, because you have claustrophobia (fear of enclosed spaces) or have certain metal implants or a pacemaker in your body.
• You have an abnormality or problem inside the brain (such as bleeding, inflammation, or unusual structural findings) that the study doctor thinks may put you at risk — though some specific MRI findings may be watched over time rather than automatically disqualifying you (confirm with trial site).
• You have a medical reason why you cannot receive a specific type of brain scan called a florbetapir F 18 PET scan.
• You have previously received any amyloid-targeting treatment outside of clinical trials involving the drug donanemab.
• You have taken part in another clinical trial involving a study treatment in the last 30 days, where that treatment may not be compatible with this study.

Important: Always verify eligibility with the trial site directly before applying.