Phase 2 Ovarian Cancer Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are 18 years of age or older
• You have a solid tumor cancer that has been confirmed by a lab test, cannot be surgically removed, has spread or is locally advanced, and has either gotten worse after standard treatments, you could not tolerate standard treatments, or no standard treatments are available for your type of cancer
• You are willing and able to provide a stored tumor tissue sample, or agree to have a tumor biopsy taken before treatment starts (for one part of the study)
• Your cancer has at least one measurable area that can be tracked on scans, according to standard measurement guidelines
• Your doctor expects you to live for more than 3 months
• You are in relatively good general health and are able to carry out normal daily activities, with little or no limitation (as measured by a standard scale used in cancer trials)
• Your bone marrow, liver, and kidneys are functioning well enough, as shown by blood tests
• You agree to follow the study's specific requirements around contraception (birth control)
• You have signed a form confirming you understand and agree to take part in the trial

Who may not be able to join:

• You have a second, separate cancer diagnosis
• Your cancer started in the brain or spinal cord, or you have cancer that has spread to the brain or spinal cord and previous local treatment there has not worked
• You have received any cancer treatment, or taken part in another treatment trial, within the past 28 days
• You have had major surgery within the past 28 days
• You still have significant side effects from previous cancer treatments that have not cleared up enough
• You have been diagnosed with a weakened immune system, or have taken immune-suppressing medications in the past 7 days
• You have other serious ongoing health conditions, as assessed by the trial doctor
• You have significant heart or blood vessel disease, as defined by the trial (confirm with trial site)
• You have an abnormally long measurement on a heart tracing (ECG) called the QTcF interval (confirm with trial site)
• You have a medical condition that is likely to affect how your body absorbs or digests the study medication
• Your blood sugar (glucose) or blood pressure is not well controlled
• Your blood potassium or sodium levels are significantly abnormal, as judged by the trial doctor
• You have had a serious infection in the 14 days before starting the study drug
• You have a confirmed infection with HIV, hepatitis B (HBV), or hepatitis C (HCV)
• You are currently taking part in another clinical trial involving an investigational treatment
• You have previously been treated with a type of drug called a CDK2 inhibitor
• You have a known allergy or sensitivity to the study drug or any of its ingredients
• You have had an organ transplant or tissue transplant from another person
• You are unwilling or unable to follow the procedures required by the study
• You have other serious health conditions, or there are other reasons the trial doctor considers you unsuitable for the study

Important: Always verify eligibility with the trial site directly before applying.