Osteoarthritis Trial, Recruiting NCT07625150 Sponsor: University of California, San Francisco Condition: Osteoarthritis
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Osteoarthritis Trial, Recruiting

NCT07625150
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults who are able to make their own decision to take part and provide consent
  • People who are able to perform 25 single-leg squats
  • People who have not had a traumatic knee injury or knee surgery since their last visit in the related parent study (IRB #21-34763)
  • People who have not taken any experimental/investigational drugs since their last visit in the related parent study (IRB #21-34763)
  • People who have no reasons that would prevent them from having an MRI or receiving the PET tracer since their last visit in the related parent study (IRB #21-34763)
  • People who are not currently receiving steroid injections
  • People who are not pregnant
  • For healthy volunteers specifically: People who report little to no pain (rated 0 or 1 on a standard pain scale) during 25 single-leg squats on one or both legs

Who may not be able to join:

  • People who are not able to make their own decision to consent to taking part
  • People who are unable to perform 25 single-leg squats on the study leg
  • People who have had a new traumatic knee injury or knee surgery since their last visit in the related parent study (IRB #21-34763)
  • People who have taken experimental/investigational drugs since their last visit in the related parent study (IRB #21-34763)
  • People who have developed new reasons preventing them from having an MRI or receiving the PET tracer since their last visit in the related parent study (IRB #21-34763)
  • People who are currently receiving steroid injections
  • People who are pregnant
  • People who have diabetes
  • For healthy volunteers specifically: People who rate their pain as 2 or higher on a standard pain scale during 25 single-leg squats on both legs

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 21 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Richard Souza, PhD, PT, University of California, San Francisco

Phone: 415-502-6470

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
19 February 2025
Est. completion
1 February 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Maximum Standardized Uptake Value (SUVmax) of [18F]FDG in PFJ Tissues, Pre-Loading; Maximum Standardized Uptake Value (SUVmax) of [18F]FDG in PFJ Tissues, Post-Loading

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov