Phase 2 Interstitial Lung Disease Trial, Recruiting NCT07652658 Sponsor: AstraZeneca Condition: Interstitial Lung Disease
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Phase 2 Interstitial Lung Disease Trial, Recruiting

NCT07652658
Recruiting Phase 2 🇦🇺 Australian site

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are 40 years of age or older
  • People who have been diagnosed with Idiopathic Pulmonary Fibrosis (IPF), a type of lung scarring disease
  • People with IPF who are either currently taking an approved anti-scarring medication at a steady, unchanged dose, or who are not currently taking any standard treatment for IPF
  • People whose lungs are still functioning at 45% or more of the expected normal level, based on a breathing test called FVC
  • People whose lungs are still able to transfer oxygen into the blood at 25% or more of the expected normal level, based on a test called DLCO (confirm with trial site)

Who may not be able to join:

  • People who have a different type of lung scarring disease other than IPF
  • People whose chest scans show more emphysema (air trapping damage) than lung scarring
  • People who are currently experiencing a sudden worsening of their IPF symptoms
  • People who currently have a lower airway or lung infection that requires treatment
  • People who have recently had a heart attack, unstable chest pain, or a heart procedure such as a stent or bypass surgery
  • People who have heart failure
  • People who have previously had an organ transplant, or for whom a lung transplant is being considered in the near future

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: 1-877-240-9479

Australian sites

Research Site, Port Macquarie,
Research Site, Wollongong,

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Registry
ClinicalTrials.gov
Start date
11 June 2026
Est. completion
14 September 2028

Where this trial is recruiting

🇦🇷 Argentina 🇦🇺 Australia 🇧🇬 Bulgaria 🇨🇦 Canada 🇨🇱 Chile 🇨🇳 China 🇩🇰 Denmark 🇫🇷 France 🇩🇪 Germany 🇬🇷 Greece 🇭🇺 Hungary 🇮🇱 Israel 🇮🇹 Italy 🇯🇵 Japan 🇲🇽 Mexico 🇵🇱 Poland 🇿🇦 South Africa 🇰🇷 South Korea 🇪🇸 Spain 🇹🇼 Taiwan 🇬🇧 United Kingdom 🇺🇸 United States

2 site(s) in Australia. Confirm current status and contact details directly with the trial site.

Primary endpoints

To evaluate the clinical efficacy of AZD8965 compared with placebo on the absolute change from baseline in FVC in mL at Week 24

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov