Phase 3 Glaucoma Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are 18 years of age or older
• You have been diagnosed with a type of glaucoma called primary open-angle glaucoma, or with high eye pressure (ocular hypertension), in both eyes
• Both of your eyes need treatment, and you are able to stop or switch your current eye pressure medications for a set period before the study begins
• Your eye pressure at the start of the trial falls within a specific range (not too low or too high), and the pressure in both eyes is similar to each other
• Your eye condition is likely manageable with just one medication
• Your vision (with glasses or contacts if needed) is at least 20/100 or better in each eye
• You are willing and able to give your consent freely and follow the study instructions
• You have no history of drug dependence, recreational drug addiction, or alcohol addiction
• If you are a woman who could become pregnant, you are using an effective form of contraception throughout the study, such as: hormonal contraception (pill, injection, patch, or implant) used consistently for at least 1 month beforehand; an IUD or similar device; a double barrier method (e.g., condom plus diaphragm or spermicide); a partner who has had a vasectomy at least 6 months ago; your own surgical sterilisation at least 6 weeks ago; or complete abstinence from sex

Who may not be able to join:

• You are pregnant, breastfeeding, or planning to become pregnant
• You have a known allergy or sensitivity to bimatoprost or similar medications, or to any ingredients in the study formula including benzalkonium chloride
• You have a current or past history of serious liver or kidney disease
• You have had a significant eye condition in either eye in the last 3 months, such as corneal swelling, eye inflammation, eye infection, or eye injury (note: stable short-sightedness, squint, or cataracts may still be acceptable — confirm with trial site)
• You have a corneal (front of the eye) abnormality that would make it difficult to accurately measure your eye pressure
• You have meaningful loss of your field of vision as measured by a vision test
• You have had a corneal transplant (corneal graft)
• You cannot have your pupils dilated (widened) for medical reasons
• You have ever had a corticosteroid implant placed inside your eye
• You have worn contact lenses within 1 week before the start of the trial
• You have used eye drop steroids or skin/body steroids in the 21 days before the start of the trial
• You have had a steroid injection into or around the eye in the 6 months before the start of the trial
• You have had eye surgery (e.g., cataract surgery) in the 3 months before the start of the trial
• You have previously had surgery or laser treatment to lower eye pressure (e.g., laser trabeculoplasty), or laser eye surgery for vision correction at any time
• You have previously tried bimatoprost and it did not work for you
• You have noticeable eye surface problems such as redness or irritation in either eye
• You have severe glaucoma with significant damage to the optic nerve (a cup-to-disc ratio greater than 0.8, unless considered normal by the doctor)
• You are taking certain long-term medications that can affect eye pressure and your dose has not been stable for at least 2 months (confirm with trial site)
• Your central corneal thickness (a measurement of the thickness of the front of your eye) is outside a specific range (confirm with trial site)
• You have an uncontrolled ongoing health condition
• You have had recurring seasonal eye allergies in the past 2 years
• You have participated in another clinical trial within the last 30 days
• You have active Hepatitis B, Hepatitis C, or HIV infection
• You have a condition where your eye has no natural lens (aphakia), or you have a history of a specific type of eye herpes infection (herpes simplex keratitis)
• You have any other medical condition that the trial doctor believes would make participation unsafe or difficult for you

Important: Always verify eligibility with the trial site directly before applying.