Phase 2 Schizophrenia Trial, Recruiting NCT07680946 Sponsor: TG Therapeutics, Inc. Condition: Schizophrenia
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Phase 2 Schizophrenia Trial, Recruiting

NCT07680946
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People with a primary diagnosis of schizophrenia.
  • People whose schizophrenia has not responded well to previous treatments (sometimes called "treatment-resistant" schizophrenia).
  • People who need antipsychotic medication and are currently receiving standard treatment for their condition.
  • People whose symptom severity scores fall within a specific range on a standard schizophrenia assessment scale (a score between 80 and 120) at the time of screening and at the start of the trial.

Who may not be able to join:

  • People who have a primary mental health diagnosis other than schizophrenia, as defined by the current standard diagnostic guidelines (DSM-5-TR).
  • People who are currently being treated with a medication called clozapine.
  • People who are considered to be at risk of suicidal behaviour.
  • People who have a serious or poorly controlled physical health condition that could affect their ability to take part in the trial.

Important: This trial may have additional eligibility requirements not listed here. Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: 1-877-575-8489

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
TG Therapeutics, Inc.
Registry
ClinicalTrials.gov
Start date
3 July 2026
Est. completion
1 December 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Percentage of Participants with at Least 20% Reduction From Baseline in PANSS Total Score

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov