Phase 3 Stroke Trial, Recruiting NCT07688551 Sponsor: University of South Carolina Condition: Stroke
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Phase 3 Stroke Trial, Recruiting

NCT07688551
Recruiting Phase 3

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are willing and able to give informed consent to participate in the study
  • People who are willing and able to follow the study requirements throughout the trial
  • People between the ages of 25 and 80 years old
  • People who have used English as their main language for more than 15 years
  • People who have been diagnosed with aphasia (difficulty with language) caused by a stroke on the left side of the brain, confirmed by a study doctor using a past or recent brain scan
  • People who are more than 6 months past the date of their stroke
  • People who have been diagnosed with a specific type of aphasia called Broca's aphasia, based on results from a standardised language test called the WAB-R, with specific scores across fluency, comprehension, repetition, and naming
  • People who correctly name 140 or fewer items on a picture naming test called the Philadelphia Naming Test (PNT)

Who may not be able to join:

  • People who have had brain surgery, other than surgery performed as part of emergency stroke treatment
  • People who have had seizures (fits) in the past 12 months
  • People who have skin problems such as rashes, eczema, wounds, or infections on or near where electrodes would be placed on the head
  • People who correctly name more than 140 out of 175 items on the pre-treatment Philadelphia Naming Test
  • People whose WAB-R Aphasia Quotient score is 25 or below (a measure of overall language ability)
  • People who have an opening in the skull larger than 1 cm in the area where an electrode would be placed, or who have metal implants or electrical devices in the body (confirm with trial site)
  • People who require continuous oxygen therapy that cannot be paused for more than one hour
  • People with any other condition or situation that the lead researcher determines would significantly interfere with completing the study

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 19 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: 803-216-3469

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Sponsor
University of South Carolina
Registry
ClinicalTrials.gov
Start date
31 July 2026
Est. completion
1 March 2030

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Naming

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 19 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov