Phase 1 Ovarian Cancer Trial, Recruiting NCT07690189 Sponsor: TeneoSeven, Inc. Condition: Ovarian Cancer
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Phase 1 Ovarian Cancer Trial, Recruiting

NCT07690189
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 18 years or older
  • People who have a confirmed diagnosis of ovarian cancer, specifically high-grade serous, high-grade endometrioid, low-grade serous, or clear cell ovarian cancer, or carcinosarcoma of the ovary (note: mucinous carcinoma of the ovary does not meet this criterion)
  • People whose ovarian cancer has come back or stopped responding to treatment, and who have already received the standard treatments known to help — this includes cancer that has stopped responding to platinum-based chemotherapy, become resistant to it, or returned after it, provided there is clear documented medical reason why further platinum chemotherapy is not suitable
  • People who are able to understand what the study involves and are willing to sign a written consent form agreeing to take part
  • People of childbearing potential who are willing to use effective contraception throughout the study and for a set period of time after the last dose of the study treatment

Who may not be able to join:

  • People who have another active cancer that could make it difficult to assess how well the study treatment is working
  • People who have recently received another experimental drug or certain other cancer treatments within a specified period before the study would begin (confirm exact timeframes with trial site)
  • People who are currently pregnant or breastfeeding

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 15 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: 510-392-0929

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Sponsor
TeneoSeven, Inc.
Registry
ClinicalTrials.gov
Start date
29 June 2026
Est. completion
1 June 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Number of dose-limiting toxicities (DLTs) within the first cycle of treatment with NTB-928; Number of participants with adverse events (AEs) and serious adverse events (SAEs), by severity and relatedness to NTB-928; Maximum plasma concentration (Cmax); Time to Cmax (Tmax); Area under the plasma concentration-time curve (AUC) over the dosing interval (AUC0-T); AUC from time zero to time t (AUC0-t); AUC from time 0 extrapolated to infinity (AUC0-∞); Terminal elimination half-life (t½); Clearance (CL); Terminal elimination rate constant (λz); Volume of distribution (Vz); Accumulation ratio (Rac)...

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 15 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov