Phase 3 Eczema Trial, Recruiting NCT07690371 Sponsor: Nektar Therapeutics Condition: Eczema
Back to Eczema

Phase 3 Eczema Trial, Recruiting

NCT07690371
Recruiting Phase 3

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 12 or older on the day they sign the consent form, and who weigh at least 40 kg before the study begins
  • People who have had atopic dermatitis (a type of chronic skin condition causing redness, itching, and inflammation) for at least 12 months before their screening appointment
  • People whose atopic dermatitis has been assessed by a doctor as moderately severe or worse, based on three specific skin scoring measurements taken at both the screening and baseline appointments (confirm with trial site for exact score details)
  • People whose atopic dermatitis has not responded well enough to existing creams or ointments within the past 6 months, or who have had problems tolerating a topical (applied to the skin) treatment — with this documented by a doctor
  • People who are willing to provide written consent to take part and follow the study procedures, including using reliable contraception as required

Who may not be able to join:

  • People who have, or have had, other skin conditions alongside their atopic dermatitis, including skin infections in the affected area that need treatment with antibiotic or antifungal tablets or injections
  • People who have, or have had, an unstable or unpredictable pattern of atopic dermatitis
  • People who have ever had long-term unexplained hives (a skin reaction causing raised, itchy welts), or who have had hives from any cause within 4 weeks before the study start
  • People whose history of using steroid creams or ointments suggests there may be a high risk of problems if those treatments were stopped
  • People who have ever received certain specific treatments before screening, including a medicine called aldesleukin, experimental versions of a protein called IL-2, biological medicines given by injection or infusion for any condition, oral JAK inhibitor medicines, or any experimental treatment for atopic dermatitis (confirm with trial site for the full list)
  • People who currently have, or have recently had, an active infection

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: 855-482-8676

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Sponsor
Nektar Therapeutics
Registry
ClinicalTrials.gov
Start date
1 July 2026
Est. completion
1 May 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

US only: Number of participants with an Investigator's Global Assessment (IGA) score of 0 or 1 and reduction ≥ 2 points from baseline at Week 24; Non-US regions only: Number of participants with an Investigator's Global Assessment (IGA) score of 0 or 1 at Week 24; Non-US regions only: Number of participants with a ≥ 75% reduction in Eczema Area and Severity Index (EASI) score from baseline at Week 24 (EASI-75)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov